Optoelectronic Methodology Suitable for Electroretinographic Investigations during Environmental Stress.
Abstract
A workable optoelectronic arrangement suitable for biomedical investigation in the field of electroretinography (ERG) was devised and is explained. ERGs were obtained in a nontraumatic manner from rhesus monkeys in an altitude chamber and under acceleration. The rhesus monkeys were exposed to a sequence of diffused flashes of light. Silver-silver-chloride electrodes attached to the monkey's head were used to pick up the electroretinal signals caused by the flashes of light. The active electrode was attached to the lower eyelid with the reference electrode at the ipsilateral ear and the ground electrode at the lateral canthus. The electroretinal signals were amplified recorded and then analyzed, using an averaging technique. Self-explanatory schematics detail the arrangement and type of instrumentation used. Cerebral oxygen tissue partial pressure (PO2) data, determined by an invasive polarographic method, were collected simultaneously with the ERG to search for a correlation between the two items. Eye safety considerations show that the flashes of light were of an intensity which is considered safe for non-human primates as well as for human subjects for an unlimited experimentation exposure time. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1980
- Accession Number
- ADA094126
Entities
People
- Abbott T. Kissen
- Alva A. Karl
- David A. Ratino
- Diana R. Nelson
- Radames K. H. Gebel