Biological Effects of Short, High-Level Exposure to Gases: Ammonia

Abstract

This report presents an analysis and synthesis of the available literature concerned with possible health and performance effects of exposures to ammonia. The US Army's concern is with short, high-level exposures that may exceed present threshold limit values of the American Conference of Governmental Industrial Hygienists (25 ppm or 17 mg/cum as a TWA and a ceiling of 35 ppm or 24 mg/cum for 15 minutes). The organs primarily affected by exposure to ammonia gas are the respiratory tract and the eyes. During brief exposures to concentrations of 500 ppm (348 mg/cum) or less, the biologic responses are immediate, reversible, and mainly irritant. Below 50 ppm (35 mg/cum), there are no significant effects except that the odor of ammonia is detectable. Between 50-100 ppm (35-70 mg/cum), most people experience some degree of irritation of the eyes, nose and throat. There is some evidence indicating that personnel may become acclimated to the irritant effects after only 1 or 2 weeks of intermittent exposure at these levels. Around 130 ppm (90 mg/cum), approximately half of exposed personnel experience lacrimation. Lacrimation has been reported in subjects inhaling 500 ppm (348 mg/cum) of ammonia via face mask, which should have prevented direct contact of ammonia with the eyes.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1980
Accession Number
ADA094501

Entities

People

  • Llewellyn J. Legters

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Blood
  • Carbon Monoxide
  • Cells
  • Dielectric Gases
  • Health Services
  • Heart Rate
  • Leukocytes
  • Lung Diseases
  • Medical Personnel
  • Nitrogen Oxides
  • Nose
  • Respiration Disorders
  • Rodents

Readers

  • Analytical Chemistry
  • Toxicology/Environmental Toxicology