Bacterial Motility: A Component in Experimental Pseudomonas aeruginosa Burn Wound Sepsis

Abstract

Mutants which do not spread in soft agar were derived from a rat burn wound virulent strain of Pseudomonas aeruginosa. When inoculated on to rat burn wounds, these motility-altered strains had significantly reduced virulence. Control agar-spreading isolates that had undergone the same manipulations were found to have maintained virulence. Other than motility, no other parental characteristic was found to be altered. The non-spreading isolates were virulent when inoculated below the burn wound. It is concluded that motility is an important factor in experimental burn wound sepsis.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1979
Accession Number
ADA094879

Entities

People

  • A. D. Mason
  • A. T. Mcmanus
  • E. E. Moody

Organizations

  • United States Army Institute of Surgical Research

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anti-Infective Agents
  • Burns
  • Cell Membrane
  • Cells
  • Dilution
  • Diseases And Disorders
  • Electron Microscopy
  • Health Services
  • Infection
  • Inoculation
  • Microbiology
  • New York
  • Production
  • Toxicity
  • Virulence
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Microbial Pathology
  • Trauma Surgery or Emergency Medicine.