Response of Combined Electrical Stimulation and Biodegradable Ceramics.
Abstract
Investigations on rod and granular forms of porous tricalcium phosphate ceramic for the surgical correction of bone lesions have been extended to segmental replacements at the mid-radii position in dogs and nonunions of rabbit tibias. Two year follow up studies on rod form implants along dog radii show the presence or residual ceramic and incomplete anatomical remodeling. Relative ceramic to iliac crest bone ratios of 100/0, 50/50, and 0/100 percent by weight showed callus bridging of 8mm. surgically created rabbit tibia defects at 14-16, 6, and 4-6 weeks respectively for the ceramic/bone filled lessions. Nonunions of rabbit tibias subjected to similar ratios of ceramic and bone showed 3 of 8 bridged for 100/0 ratio, 2 to 6 bridged at 50/50 ratio looked much better than the total ceramic implants. In all cases, the tissue reactions to the porous tricalcium phosphate ceramic showed good biocompatibility. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1979
- Accession Number
- ADA095533
Entities
People
- Jack E. Lemons
Organizations
- University of Alabama