The Association-Induction Hypothesis and Physiological Excitation.

Abstract

The electrical potential at the boundary of the outside and inside of biological cell phases is studied on the basis of the Association-Induction Hypothesis. According to the latter the cell interior contains fixed sites, in the side chains and at the backbones of proteins at which biologically active substances, like ions are specifically adsorbed. Equations have been derived to determine the profile of the electrical potential at the phase boundary of the cell. They are to be solved when solutions to the wave mechanical problems described below will have been obtained. As the protein sites are interconnected cooperative mechanisms are involved which are due to inductive interactions. The basis of these interactions is wave mechanical. A method is used to determine the changes in the charge densities of the localized electrons as well as the conformational changes in proteins. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Jan 27, 1981
Accession Number
ADA096108

Entities

People

  • George Karreman

Organizations

  • University of Pennsylvania

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Amino Acids
  • Atomic Orbitals
  • Biological Processes
  • Boundaries
  • Boundary Layer
  • Cell Membrane
  • Cells
  • Charge Density
  • Differential Equations
  • Electrons
  • Equations
  • Ions
  • Mechanics
  • Membranes
  • New York
  • Software In The Loop
  • Statistical Mechanics

Readers

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  • Structural Dynamics.
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Technology Areas

  • Microelectronics
  • Microelectronics - Microelectromechanical Systems