An Improved Synthesis of Bis(Trimethylsilyl)-Chloromethane.
Abstract
A new 'one pot' synthesis of the important intermediate (Me3Si)2CHC1, is described. The method involves the reaction of CH2CL2, Me3SiC1, and n-BuLi in a mixed solvent system. The overall yield of (Me3Si)2CHC1 based upon the CH2C12 consumed is 78%. Apart from the obvious advantage of being a single step procedure, the method also has the advantage of utilizing relatively inexpensive starting materials. Moreover, the method can be scaled up without significant diminution of the yield. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 11, 1981
- Accession Number
- ADA097210
Entities
People
- A. H. Cowley
- R. A. Kemp
Organizations
- University of Texas at Austin