Increased Renal Perfusion and Kidney Size in Convalescent Burn Patients

Abstract

Renal blood flow was elevated in convalescent burn patients shortly before discharge (992 + or - 112 mL/min/sq m in burn patients vs 551 + or - mL/min/sq m in normal subjects; mean + or - SE). Autopsy studies demonstrated that renal enlargement was a constant feature of patients after a prolonged hospital course; the kidneys of 28 patients who died after 60 days of hospitalization weighed 241 + or - 10 g vs 153 + or - 8 g in control subjects. The increase in renal weight was primarily related to cellular hypertrophy and hyperplasia. These physiological and morphological findings in thermally injured patients may be a form of renal work hypertrophy following increased protein catabolism accompanying severe injury.

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Document Details

Document Type
Technical Report
Publication Date
Oct 03, 1980
Accession Number
ADA097510

Entities

People

  • Cleon W. Goodwin
  • Douglas W. Wilmore
  • Louis H. Aulick
  • Richard A. Becker

Organizations

  • United States Army Institute of Surgical Research

Tags

DTIC Thesaurus Topics

  • Blood
  • Blood Flow
  • Burns
  • Health Services
  • Hospitals
  • Hypertrophy
  • Infusions
  • Kidneys
  • Myocardial Ischemia
  • Necrosis
  • Statistical Analysis
  • Thermal Burns
  • Vascular Congestion
  • Veins

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Trauma or Military Medicine