Percutaneous Toxicokinetics of Hydrazine and H-70 in the Rabbit

Abstract

The percutaneous absorption of anhydrous hydrazine and H70 (70% hydrazine) has been studied. The half life of hydrazine in the rabbit was determined to be 2.3 hours. The absorption half life for both anhydrous hydrazine and H70 was estimated to be 10-20 minutes. Anhydrous hydrazine was absorbed to a greater extent (86%) than hydrazine as H70 (55%). The extent of percutaneous absorption in the rabbit appears to be greater than that in the dog.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 1981
Accession Number
ADA097954

Entities

People

  • James P. F. Murphy
  • Kenneth C. Back
  • Melvin E. Andersen
  • William C. Keller

Organizations

  • Air Force Research Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Aerozine
  • Air Force
  • Biomedical Research
  • Blood
  • Burns
  • Chemical Burns
  • Composite Materials
  • Epidermis
  • Equations
  • Hazards
  • Hydrazines
  • Laboratory Animals
  • Measurement
  • Medical Personnel
  • Pharmacology
  • Toxic Hazards
  • Toxicology

Readers

  • Organic Chemistry
  • Toxicology/Environmental Toxicology