Korean Hemorrhagic Fever: Propagation of the Etiologic Agentina Cell Line of Human Origin

Abstract

The etiologic agent of Korean hemorrhagic fever has been propagated in a human cultured cell line derived from a carcinoma of the lung. The cells, described as type II, alveolar epithelial, support replication of the agent and successive passages. Antigen of the Korean hemorrhagic fever agent is readily detected in infected cells by means of direct or indirect fluorescent antibody techniques. Previous attempts to propagate agent in vitro had been unsuccessful.

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Document Details

Document Type
Technical Report
Publication Date
Mar 06, 1981
Accession Number
ADA100071

Entities

People

  • George R. French
  • Gerald A. Eddy
  • Ho Wang Lee
  • Orville A. Brand
  • Richard S. Foulke

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Antibodies
  • Biomedical Research
  • Blood
  • Cell Line
  • Cells
  • Culture Techniques
  • Cultured Cells
  • Geographic Regions
  • Infection
  • Inoculation
  • Laboratory Animals
  • Materials
  • Monkeys
  • Owl Monkeys
  • Tissues
  • Wound Infections

Fields of Study

  • Medicine

Readers

  • Virology (or Medical Virology).