Use of Activated Charcoal for Hemoperfusion in Dutch Rabbits
Abstract
Techniques for a hemoperfusion system with activated charcoal have been developed for studying circulatory detoxification in Dutch rabbits. During a period of 8 hours of hemoperfusion, mean arterial blood pressure, heart rate, hematocrit, RBA fagility, plasma protein concentration, plasma osmolality, leukocyte and platelet counts, and rectal temperature did not show significant changes as compared with prehemoperfusion (base-line) values. All 5 tested rabbits survived after prolonged hemoperfusion, indicating that the present system is safe for use in rabbits.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 14, 1980
- Accession Number
- ADA100073
Entities
People
- C. T. Liu
- E. J. Galloway
Organizations
- United States Army Medical Research Institute of Infectious Diseases