Topical Hazard Evaluation Program of Candidate Insect Repellents US Department of Agriculture Proprietary Chemicals Study, October 1978 - April 1981.

Abstract

Preliminary hazard evaluation of the above candidate insect repellent chemicals were performed by means of laboratory animal studies using rats, rabbits, and guinea pigs. Chemicals AI3-37330a, 37339a, and 37350a were noninjurious to the eyes of rabbits. Chemicals AI3-37332a, 37343a, 37346a, and 37349a caused mild injury to the cornea and, in addition, some injury to the conjunctiva. All of the chemicals did not cause skin or photoirritation, and did not prove to be skin sensitizers. Chemicals AI3-37343a and 37349a were moderately toxic by ingestion. The remaining chemicals were relatively nontoxic by ingestion. It was recommended that all chemicals be approved for further testing as candidate insect repellents. (Author)

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jun 11, 1981
Accession Number
ADA100411

Entities

People

  • John G. Harvey
  • Michael J. Topper

Organizations

  • United States Army Medical Command

Tags

DTIC Thesaurus Topics

  • Abrasion
  • Agriculture
  • Animals
  • Biological Laboratories
  • Digestive System Processes
  • Eye
  • Health
  • Health Services
  • Hygiene
  • Insect Repellents
  • Irritation
  • Laboratory Animals
  • Lagomorphs
  • Lethal Dosage
  • Pest Control
  • Physical Properties
  • Rodents

Readers

  • Toxicology/Environmental Toxicology