The Mutagenic Potential of 4-Nitrophenyl methyl Phenyl Phosphinate, 4- Nitrophenyl Diphenyl Phosphinate, 4-Nitropehenyl Dimethyl Phosphinate, 4- Chlorophenyl Methyl Phenyl Phosphinate, 4-Chlorophenyl diphenyl Phosphinate

Abstract

The Mutagenic Potential of 4-nitrophenyl methyl phenyl phosphinate; 4-nitrophenyl diphenyl phosphinate; 4-nitrophenyl dimethyl phosphinate; 4- chlorophenyl methyl phenyl phosphinate; 4-chlorophenyl diphenyl phosphinate was assessed using the Ames Salmonella/Mammalian Microsome Mutagenicity Assay. Tester Strains TA 98, TA 100, TA 1535, TA 1537, TA 1538 were were exposed to doses ranging from 0.01 mg/plate to .0000032 mg/plate for 4-chlorophenyl diphenyl phosphinate and 1 mg/plate to .00032 mg/plate for all other test compounds. It was determined that none of the tested substances had mutagenic potential.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1981
Accession Number
ADA103139

Entities

People

  • Freddica R. Pulliam
  • John T. Fruin
  • Leonard J. Sauers

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  • Letterman Army Hospital

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  • Biomedical

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  • Biomedical Research
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  • Agricultural and Food sciences

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  • Organic Chemistry
  • Toxicology/Environmental Toxicology