Behavioral Effects of Atropine and Benactyzine: Man-Monkey Comparisons.

Abstract

Dose-response curves for atropine- or benactyzine-induced performance decrements were estimated for both humans and monkeys. Monkeys were more tolerant than humans to both drugs, and their dose-response curves were not as steep. Thus, no simple correction coefficient would allow extrapolation of data from one species to the other. However, rough extrapolations could be made for specific levels of performance decrement by using the regression equations or graphs developed from the data analysis. (Author)

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1981
Accession Number
ADA103328

Entities

People

  • C. Thomas Bennett
  • Donald N. Farrer
  • Joel L. Mattsson

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Aerospace Medicine
  • Air Force
  • Air Force Facilities
  • Atropine
  • Central Nervous System
  • Enzyme Inhibitors
  • Equations
  • Government Procurement
  • Governments
  • Incapacitation
  • Nerve Agents
  • Nervous System
  • Platforms
  • Reaction Time
  • Task Performance And Analysis
  • United States
  • Weapons

Fields of Study

  • Biology

Readers

  • Regression Analysis.
  • Toxicology/Environmental Toxicology