Effect of Ionizing Radiation on Shock-Elicited Aggression of Male Rats.

Abstract

Several pairs of male Sprague-Dawley rats were exposed to either 0, 350, 700, 1400, or 2100 rads of Co60 radiation at 250 rads/min. Pairs were then tested for aggression at 20 min, 6 h, 72 h, and 7 d post irradiation. Each test session lasted for 5 min and consisted of 50 3-W shocks 0.5-s duration with a 5.5-s shock-shock interval. Scores indicated how many aggressive interactions took place during the 50 intershock intervals. Aggressive interactions in the 700-rad group increased (p <,025) at 72 h post irradiation. Secondarily, to validate the experimental procedure, a known aggression-reducing drug was tested on a different set of rats. Chlorpromazine hydrochloride, 2 mg/kg, intramuscular, caused a decrease in aggression 120 min post injection (p <.01). (AUTHOR)

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1981
Accession Number
ADA103329

Entities

People

  • Joel L. Mattsson
  • Joseph R. Fischer
  • Robert D. Burke Jr.

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

Communities of Interest

  • Biomedical
  • Space

DTIC Thesaurus Topics

  • Aerospace Medicine
  • Air Force
  • Air Force Facilities
  • Analysis Of Variance
  • Animals
  • Gamma Rays
  • Government Procurement
  • Governments
  • Histamine
  • Intervals
  • Ionizing Radiation
  • Laboratory Animals
  • Radiation
  • Radiation Effects
  • Security
  • Statistical Analysis
  • X Rays

Fields of Study

  • Biology
  • Psychology

Readers

  • Mathematics or Statistics
  • Nuclear and Radiation Engineering.
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.