Synthesis of 6-Substituted-2,4-Diamino-5,6,7,8-Tetrahydropyrimido (4-5-d) Pyrimidines. Revised.

Abstract

A series of sixteen target compounds involving primarily methylene ethylene and methyleneoxy spacers between the heterocyclic portion and halogenated phenyl portion were prepared and submitted for screening. The chemistry and biological screening results are described. None of the compounds exhibited useful chemotherapeutic activity. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1981
Accession Number
ADA104571

Entities

People

  • Diane D. Kirt
  • Salah M. Sami
  • Thomas J. Delia

Organizations

  • Central Michigan University

Tags

DTIC Thesaurus Topics

  • 2-Ring Heterocyclic Compounds
  • Acids
  • Amines
  • Biological Pigments
  • Chemical Compounds
  • Chemical Synthesis
  • Chemistry
  • Enzyme Inhibitors
  • Imines
  • Materials
  • Organic Chemistry

Fields of Study

  • Chemistry

Readers

  • Organic Chemistry
  • Parasitology and Pharmacology of Malaria.