Cryopreservation of Schistosome Larvae.
Abstract
A wide range of intraspecific genetic variations has been demonstrated in both S. mansoni and B. glabrata: 21 strains of S. mansoni showing 17 different patterns of snail infectivity, and 20 stocks of B. glabrata with 16 different patterns of parasite susceptibility are under study. Snail crosses demonstrated several genetic factors determining adult susceptibility. Seven Puerto Rican stocks of B. glabrata apparently differ genetically in susceptibility patterns. S. mansoni crosses have demonstrated several different snail infectivity factors, some dominant and some recessive. Mouse immunogenicity studies have demonstrated a significant difference between two S. mansoni substrains from an isolate from a Puerto Rican chronic case, one substrain giving high protection, one low. S. mansoni substrains from a Puerto Rican chronic case showed good immunogenicity in unisexual infections. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 1981
- Accession Number
- ADA105631
Entities
People
- C. S. Richards
- M. A. Stirewalt