Primary Dermal Irritation Potential of Components of the M-258A-1 Decontamination Kit (Study 1).

Abstract

The dermal irritation potential of components of the Prototype M-258A-1 decontamination kit was assessed by using the modified Draize test. The test called for approximately 0.5 g of material to be held in contact with the skin of rabbits for 24 hr. Both components, Decon I and Decon II, when applied separately and together caused severe erythema and necrosis after 24 hr. Further testing of these components is recommended to determine if they present a significant hazard. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1981
Accession Number
ADA105977

Entities

People

  • John T. Fruin
  • Martha A. Hanes

Organizations

  • Letterman Army Hospital

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Arteries
  • Biological Sciences
  • Biomedical Research
  • Blood
  • Cells
  • Chemical Warfare
  • Chemical Warfare Agents
  • Connective Tissue
  • Decontamination Kits
  • Epidermis
  • Hydroxides
  • Medical Personnel
  • New Zealand
  • Skin
  • Skin Diseases
  • Tissues
  • United States

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