The Mutagenic Potential of 4 nitrophenyl bis(2-thienyl)-phosphinate; 4-nitrophenyl 2-furyl(methyl)-phosphinates; 4-cyanophenyl bis(2-furyl)-phosphinate; 4-nitrophenyl bis(2-furyl)-phosphinate.

Abstract

The mutagenic potential of 4 nitrophenyl bis(2-thienyl)phosphinate (41); 4-nitrophenyl 2-furyl(methyl)phosphinate (72) 4 cyanophenyl bis(2-furyl)phosphinate (82); 4-nitrophenyl bis(2-furyl)phosphinate (87) was assessed by using the Ames Salmonella/Mammalian Microsome Mutagenicity Assay. Tester strains TA 98, TA 100, TA 1535, TA 1537 and TA 1538 were exposed to doses ranging from 1 mg/plate to .00032 mg/plate. It was determined that none of the tested substances had mutagenic potential. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1981
Accession Number
ADA105978

Entities

People

  • Freddica R. Pulliam
  • John T. Fruin
  • Leonard J. Sauers

Organizations

  • Letterman Army Hospital

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anatomy
  • Biological Sciences
  • Biology
  • Biomedical Research
  • California
  • Cells (Biology)
  • Genetics
  • Histidine
  • Military Research
  • Molecules
  • Mutagenicity Tests
  • Mutations
  • Statistical Analysis
  • Toxicity
  • United States
  • United States Government
  • Verification

Fields of Study

  • Chemistry

Readers

  • Toxicology/Environmental Toxicology