The Mutagenic Potential of: 4-fluorophenyl methyl (phenyl) phosphinate, 4-nitrophenyl 4-trifluoromethylphenyl (methyl) phosphinate, 4-nitrophenyl 3-trifluoromethylphenyl (methyl) phosphinate, 4-methylsulfinylphenyl methyl (phenyl) phospinate.

Abstract

The mutagenic potential of 4 fluorophenyl methy(phenyl)phosphinate (44*); 4-nitrophenyl 4-trifluoromethylphenyl(methyl)phosphinate (86*); 4-nitrophenyl 3-trifluoromethylphenyl(methyl)phosphinate (4*); 4-methylsulfinylphenyl methyl(phenyl)phosphinate (96*) was assessed by using the Ames Salmonella/Mammalian Microsome Mutagenicity Assay. Tester strains TA 98, TA 100, TA 1535, TA 1537 and TA 1538 were exposed to doses ranging from 1 mg/plate to 3.2 x 10 to the -4 mg/plate. It was determined that none of the tested substances had mutagenic potential. (Author)

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1981
Accession Number
ADA106055

Entities

People

  • Freddica R. Pulliam
  • John T. Fruin
  • Leonard J. Sauers

Organizations

  • Letterman Army Hospital

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Air Force Facilities
  • Biological Sciences
  • Biomedical Research
  • California
  • Genetics
  • Histidine
  • Molecules
  • Mutagenicity Tests
  • Mutations
  • Scientific Research
  • Statistical Analysis
  • Toxicity
  • Toxicology
  • United States
  • United States Government
  • Verification

Fields of Study

  • Chemistry

Readers

  • Organic Chemistry
  • Toxicology/Environmental Toxicology