The Acute Toxicity of Polyethylene Glycol 200 in Laboratory Animals.

Abstract

Mice and rats were exposed to polyethylene glycol 200 (PEG 200) aerosols by the inhalation route for 6 hours at a concentration of 2,516 mg/cu m. The LCt50 for PEG 500 is greater than the 905,760 mg min/cu m used in this study. No biologically significant alterations in blood chemistry, hematology, or pulmonary resistance were found. No mutations or pathological abnormalities could be attributed to the PEG 200 exposure. Intravenous and oral toxicity tests in rats place PEG 200 in the relatively harmless class. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1981
Accession Number
ADA106519

Entities

People

  • Aubrey E. Cooper
  • James W. Crook
  • John T. Weimer
  • Paul Hott
  • Richard L. Farrand

Organizations

  • United States Army Armament Research, Development and Engineering Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Blood
  • Blood Chemistry
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Drosophila
  • Health Services
  • Laboratory Animals
  • Medical Personnel
  • New York
  • Rodents
  • Toxicity

Readers

  • Toxicology/Environmental Toxicology