Equilibrium Performance Changes Produced by Atropine in M. mulatta and M. fascicularis.
Abstract
Two species of monkeys were trained to maintain a primate equilibrium platform in a relatively horizontal position by a control stick. Once asymptotic performance was achieved, animals received intramuscularly a saline control injection or 0.105, 0.140, 0.197, or 0.250 mg/kg, in randomized order, of atropine sulfate. The animals' performance was then observed for 3.5 hours. A statistically significant ordering of drug effects was seen, but no differences between species. Atropine produced no effect at the 0.105-mg/kg dose, but marked performance decrements were measured after the 0.250-mg/kg dose. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 1981
- Accession Number
- ADA107653
Entities
People
- C. Thomas Bennett
- Donald N. Farrer
- Joel L. Mattsson
- Neal E. Lof
Organizations
- United States Air Force School of Aerospace Medicine