Studies on the Mechanism of Action of the in vitro PGB(x) Effect. II. Reaction Medium Component Requirements for PGB(x) Effect.

Abstract

The in vitro system for the assay of the PGBx effect was investigated by exposing rat liver mitochondria (RLM) to the individual components of the normal system, as well as to all possible binary mixtures of these constituents. The degree of degradation, as measured by the decrease in absorbance at lambda 525nm, was compared with the ability of RLM to carry out oxidative phosphorylation. The results indicate there is no correlation between the PGBx effect and the effect of PGBx on the swelling of RLM.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1981
Accession Number
ADA108661

Entities

People

  • E. Soffer
  • H. W. Shmukler
  • M. G. Zawryt

Organizations

  • Naval Air Warfare Center Warminster

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Albumins
  • Biochemistry
  • Chemical Compounds
  • Classification
  • Control Systems
  • Degradation
  • Demonstrations
  • Engineering
  • Materials
  • Military Research
  • Mitochondria
  • Nucleotides
  • Numbering Systems
  • Numbers
  • Phosphorylation
  • Residuals
  • Security

Readers

  • Molecular and Cellular Biochemistry