Studies on the Mechanism of Action of the in vitro PGB(x) Effect. III. The Interaction between PGB(x) and Rat Liver Mitochondria

Abstract

Tritium labelled PGB sub x-active oligomers were synthesized by alkaline polymerization of (3)H-PGB sub 1. When added to PGB sub x assay system non-stoichiometric amount of (3)H-PGB sub 1x were bound to RLM. The degree of binding was dependent upon the concentration of (3)H-PGB sub 1x in the reaction. On the assumption that (3)H-PGB sub 1x and PGB sub x are similar or identical in structure, then no correlation between PGB sub x effect and PGB sub x binding by RLM could be found.

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Document Details

Document Type
Technical Report
Publication Date
Sep 17, 1981
Accession Number
ADA108900

Entities

People

  • Elaine F. Soffer
  • Herman W. Shmukler
  • Margaret G. Zawryt
  • Sara F. Kwong

Organizations

  • Naval Air Warfare Center Warminster

Tags

Communities of Interest

  • Air Platforms
  • Biomedical

DTIC Thesaurus Topics

  • Aircrafts
  • Alcohols
  • Chemistry
  • Engineering
  • Ethylene Glycol
  • Materials
  • Military Research
  • Mitochondria
  • Mixtures
  • New England
  • Numbering Systems
  • Numbers
  • Oligomers
  • Phosphorylation
  • Polymerization
  • Radioactivity

Readers

  • Molecular and Cellular Biochemistry