Transmission of Oropouche Virus from Man to Hamster by the Midge 'Culicoides Paraensis',

Abstract

Oropouche virus (arbovirus family Bunyaviridae, Simbu serogroup) was experimentally transmitted from man to hamster by the bite of Culicoides paraensis. Infection rates of 34% and 13% and transmission rates of 17% and 5% were observed after Culicoides engorged on patients with viremia levels of 6.3-7.3 and 5.3-6.2 log10 SMLD50/ml of blood, respectively. Threshold titer necessary to enable infection or transmission by the midges was approximately 5.3 log 10 SMLD50/ml of blood. Transmission was achieved 6 to 12 days after C. paraensis had taken the infective blood meal. This represents the first conclusive evidence of transmission of an arbovirus of public health importance to man by a member of the Ceratopogonidae family. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1981
Accession Number
ADA109916

Entities

People

  • Alfred L. Hoch
  • Ameilia P. A. Rosa
  • Francisco P. Pinheiro
  • James W. Leduc
  • Maria L. C. Gomes

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Arboviruses
  • Biomedical Research
  • Disease Outbreaks
  • Diseases And Disorders
  • Epidemiology
  • Equine Encephalitis
  • Health
  • Infection
  • Infectious Diseases
  • Insects
  • Laboratory Animals
  • Public Health
  • Universities
  • Virus Diseases
  • Viruses
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Vector-Borne Disease and Entomology
  • Virology (or Medical Virology).