Indocyanine Green (ICG) and Evans Blue: Comparative Study of Plasma Volume Measurement,
Abstract
Indocyanine green (ICG) has been used successfully to measure cardiac output, hepatic blood flow, and liver function. ICG has a low toxicity, is rapidly distributed in the blood stream, is essentially completely cleared via the liver and has a short half-life. Therefore, it seemed potentially useful for the rapid measurement and remeasurement of plasma volume in rats and, at the same time, survey any potential changes of hepatic clearance (function). This paper compares plasma, blood, and cell volumes in rats measured by ICG dilution and the classical Evans Blue method.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 08, 1981
- Accession Number
- ADA111037
Entities
People
- Denise Schehl-geiger
- Roger W. Hubbard
- William R. Sandel
Organizations
- United States Army Research Institute of Environmental Medicine