Sequential Postmortem Changes of Glomeruli. Their Detection by Scanning Electron Microscopy

Abstract

Postmortem changes were studied by scanning electron microscopy (SEM) in renal tissue from five species of animals. Specimens were collected at intervals up to 24 hours after death. Six distinct morphological alterations were identified in the renal glomerulus, including capillary loop constriction, changes in microvillus morphological features, podocyte surface blebs, swelling or fusion of pedicels, podocyte erosion, and retraction or loss of pedicels. Glomerular size remained nearly constant in all five species. The results of these studies demonstrate that pathological evaluation by SEM of tissue specimens from the kidney is acceptable up to 60 minutes post mortem.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1981
Accession Number
ADA112590

Entities

People

  • Paulette C. Langlinais

Organizations

  • United States Army Institute of Surgical Research

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Buffers (Chemistry)
  • Cellular Structures
  • Constrictions
  • Death
  • Electron Microscopy
  • Electrons
  • Glomeruli
  • Kidneys
  • Lethal Dosage
  • Membranes
  • Microscopy
  • Microvessels
  • New York
  • Observation
  • Scanning
  • Scanning Electron Microscopy

Readers

  • Cardiovascular Physiology
  • Oncology and Biomarker-Based Cancer Detection.
  • Thin Film Deposition Science.

Technology Areas

  • Microelectronics