The Mutagenic Potential of 2,4-diamino-6-(2'-napthyl-sulfonyl) quinazoline.

Abstract

The mutagenic potential of 2,4-diamino-6-(2'napthyl-sulfonyl) quinazoline (WR158122) was assessed by using the Ames Salmonella/Mammalian Microsome Mutagenicity Assay. Tester strains TA 98, TA 100, TA 1535, TA 1537 and TA 1538 were exposed to doses ranging from .001 mg/plate to 3.2 x 10 to the minus 7th power mg/plate. It was determined that the test substance did not have mutagenic potential.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 1982
Accession Number
ADA112971

Entities

People

  • John T. Fruin
  • Leonard J. Sauers

Organizations

  • Letterman Army Hospital

Tags

DTIC Thesaurus Topics

  • Acids
  • Biological Sciences
  • Biomedical Research
  • California
  • Chemical Analysis
  • Chemistry
  • Detection
  • Genetics
  • Materials
  • Mutagenicity Tests
  • Mutagens
  • Plastic Explosives
  • Scientific Research
  • Spectra
  • Toxicity
  • Toxicology
  • United States

Fields of Study

  • Agricultural and Food sciences

Readers

  • Parasitology and Pharmacology of Malaria.
  • Toxicology/Environmental Toxicology