Interaction of Methylated Adenine Derivatives with the Mercury Electrode.
Abstract
Adenine and its methylated derivatives, 1-methyl-6-aminopurine, 3-methyl-6 aminopurine, N-methyl-6-aminopurine, and N,N-dimethyl-6-aminopurine, were studied in alkaline solution by DC, normal pulse and differential pulse polarography and by cyclic voltammetry and cathodic stripping voltammetry at hanging mercury drop electrodes. All save N, N-dimethyl-6-aminopurine gave polarographic mercury drop electrodes. All save N, N-dimethyl-6-aminopurine gave polarographic currents anc cathodic stripping peaks due to the formation of slightly soluble compounds with mercury. It was concluded that the 6-amino group of adenine is the mercury binding site in these cases. Cathodic stripping behavior suggests that 1-methyl-6-aminopurine, 3-methyl-6-aminopurine, and N-methyl-6-aminopurine can be determined by cathodic stripping voltammetry, and that detection limits for N-methyl-6-aminopurine are comparable to those for adenine (10 to the minus 9th power M). (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 30, 1982
- Accession Number
- ADA114464
Entities
People
- Emil Palecek
- Janet Osteryoung
- R. A. Osteryoung
Organizations
- University at Buffalo