Two Dimensional Mass Spectrometric Separation and Identification of Complex Mixtures,

Abstract

The new technique of tandem mass spectrometry (MS/MS) has been investigated, in particular for the analysis of complex organic mixtures for trace components. Applicability, limitations, and improvements studied include those involving sensitivity, specificity, accuracy, speed, and identification of unknown components. The technique has been applied to important problems in targeted compound analysis, targeted class analysis, molecular structure determination, and unimolecular ion decomposition mechanisms. A unique tandem double-focusing mass spectrometer has been constructed, improved, and applied to these research problems. (Author)

Open PDF

Document Details

Document Type
Technical Report
Publication Date
May 10, 1982
Accession Number
ADA115202

Entities

People

  • F. W. Mclafferty

Organizations

  • Cornell University Department of Chemistry and Chemical Biology

Tags

Communities of Interest

  • Biomedical
  • Human Systems
  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Accuracy
  • Chemistry
  • Complex Mixtures
  • Decomposition
  • High Resolution
  • Identification
  • Instrumentation
  • Ionization
  • Mass Spectra
  • Mass Spectrometers
  • Mass Spectrometry
  • New York
  • Sensitivity
  • Spectra
  • Spectrometers
  • Spectrometry
  • Two Dimensional

Fields of Study

  • Chemistry

Readers

  • Oncology and Biomarker-Based Cancer Detection.
  • Organic Chemistry
  • Systems Analysis and Design