Acute Toxicity of 3,3-Diethynldiphenol Sulfone: An Acetylene Terminated Sulfone

Abstract

Acetylene terminated sulfone or 3,3-diethynldiphenol sulfone was subjected to a battery of acute animal toxicity studies for estimation of its potential health hazards to production or material handling workers. These studies included acute oral, acute dermal, eye irritation, skin irritation and skin sensitization testing. Inhalation studies could not be performed because the tacky nature of the finely ground material prevented generation of an aerosol. The fine particles rapidly clumped together forming larger and larger irregular shaped masses up to several inches in size. All of the acute toxicity tests conducted were negative at the levels tested in the animal models used, and it is probable that this material can be handled without harmful acute effects by workers using standard hygienic precautions.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1982
Accession Number
ADA115437

Entities

People

  • C. L. Gaworski
  • E. H. Vernot
  • J. D. Macewen
  • J. R. Horton

Organizations

  • University of California, Irvine

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  • Biomedical

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  • Air Force
  • Air Force Facilities
  • Alkynes
  • Animals
  • Biomedical Research
  • Body Weight
  • California
  • Contracts
  • Governments
  • Materials
  • Materials Laboratories
  • Rodents
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  • Standards
  • Toxic Hazards
  • Toxicity
  • United States

Readers

  • Polymer Science and Technology
  • Systems Analysis and Design
  • Toxicology/Environmental Toxicology