Investigations of Cross Immunity between Leishmania tropica (Jericho) and Leishmania braziliensis in Experimentally Infected Mystromys albacaudatus.

Abstract

Methods have been outlined for storage and reconstitution of various leishmania strains to be used as a vaccine. Investigation of cross immunity between L. Tropica (Jericho) and L. braziliensis panamensis were made utilizing the African white tailed rat, mystromys albacaudatus, model. It was established that an ulcerogenic dose of L. tropica (Jericho) and L. braziliensis (panamensis) was 2 x 106 promastigotes. Preliminary results indicated that L. tropica (Jericho) infected M albacaudatus may develop immunity to infection with not only the homologus strain but also against L. braziliensis panamensis. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1979
Accession Number
ADA115528

Entities

People

  • Bruce E. Beacham

Organizations

  • University of Virginia

Tags

DTIC Thesaurus Topics

  • Animals
  • Cells
  • Diseases And Disorders
  • Health
  • Immunity
  • Immunization
  • Infection
  • Infectious Diseases
  • Leishmania
  • Leishmaniasis
  • Medical Personnel
  • Parasitic Diseases
  • Parasitology
  • Protozoan Infections
  • Resistance
  • Rodents
  • Vaccination

Readers

  • Infectious Disease/Epidemiology

Technology Areas

  • Biotechnology