Hematologic Characterization of Naturally Occurring Malaria (Plasmodium inui) in the Cynomolgus Monkey (Macaca fascicularis).

Abstract

Forty-three percent of 47 recently imported cynomolgus monkeys (Macaca fascicularis) were found to have malarial infections. The agent identified was Plasmodium inui. All infections were subclinical in nature. Parasitemias ranged from 10-900 parasites/cm mm of whole blood. Pre- and posttreatment hematologic values were evaluated following treatment with chloroquine. Treatment was effective in clearing parasitemias from 13 of 14 infected monkeys. Pretreatment values of hematocrit, hemoglobin and mean corpuscular volume were significantly different in infected animals compared to noninfected animals. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Apr 23, 1982
Accession Number
ADA116839

Entities

People

  • Harry Rozmiarek
  • John C. Donovan
  • Richard D. Montrey
  • William S. Stokes

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

DTIC Thesaurus Topics

  • Animals
  • Biomedical Research
  • Blood
  • Blood Cells
  • Cells
  • Coinfection
  • Diseases And Disorders
  • Erythrocytes
  • Infection
  • Infectious Diseases
  • Laboratory Animals
  • Macaca Fascicularis
  • Parasitemias
  • Statistical Analysis
  • United States
  • Veins
  • Wound Infections

Fields of Study

  • Medicine

Readers

  • Mathematics or Statistics
  • Parasitology and Pharmacology of Malaria.
  • Toxicology/Environmental Toxicology