Studies on the Mechanism and Prevention of Decompression Sickness.

Abstract

The studies focused on three main areas: Decompression Sickness, Dysbaric Osteonecrosis and Dysbaric Alteration of the Blood-Brain Barrier. On decompression sickness, attempts were made to elucidate pathogenetic mechanisms. Several hypotheses were advanced and novel pathogenetic concepts were proposed. On the basis of new theoretical considerations we were able to develop means for the prevention or amelioration of the disease. Regarding dysbaric osteonecrosis, we developed an animal model which permitted studies on the etiology predisposition and pathogenesis of the disorder. The most recrnt investigations covered by this report involve dysbaric modification of blood-tissue barriers, an observation which was made in our Laboratories few years ago. The report includes an overview (summary) of the investigations conducted in these areas with references to pertinent publications. In lieu of detailed description of the work done, reprints to pertinent publications. In lieu of detailed description of the work done, reprints of representative articles have been attached. We hope that this material might be of help to those interested in the fields of dysbaric disroders.

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Document Details

Document Type
Technical Report
Publication Date
Jul 12, 1982
Accession Number
ADA118623

Entities

People

  • Chryssanthos Chryssanthou

Organizations

  • Beth Israel Medical Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Azo Compounds
  • Blood
  • Blood-Brain Barrier
  • Brain
  • Cardiovascular System
  • Cells
  • Chemistry
  • Decompression Sickness
  • Drug Abuse
  • Health Services
  • Medical Personnel
  • Rodents

Fields of Study

  • Medicine

Readers

  • Systems Analysis and Design
  • Technical Research and Report Writing.
  • Underwater engineering and Marine Technology.