Dermal Hazard Evaluation of Diethyl Chloroethyl Amine Underwear Fabric Treatment.

Abstract

To provide guidance for further skin testing, diethyl chloroethyl amine -- treated cotton underwear fabric was applied in patch form to the intact and abraded skin of New Zealand White rabbits. Treated cotton fabrics OD III DS 0.144 and White DS 0.079 did not cause primary skin irritation in rabbits under controlled test conditions. It was recommended that cotton fabrics reacted with diethyl chloroethyl amine to a degree of substitution (DS) of less than 0.145 mole of amine substitute/mole of cellulose monomer unit be approved for further skin testing, including prophetic human patch testing. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Aug 24, 1982
Accession Number
ADA118642

Entities

People

  • Michael J. Topper
  • Richard A. Angerhofer

Organizations

  • United States Army Medical Command

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Cellulose
  • Education
  • Fabrics
  • Guidance
  • Health Services
  • Irritation
  • Laboratory Animals
  • Maryland
  • New Zealand
  • Security
  • Test And Evaluation
  • Toxicology
  • Underwear
  • United States

Readers

  • Materials Science
  • Polymer Science and Engineering.
  • Toxicology/Environmental Toxicology