Rapid Diagnosis of Beta-Lactamase Enzyme in Penicillinase Producing Neisseria gonorrhea.

Abstract

A chromogenic cephalosporin technique and an acidometric technique to diagnose the presence of beta-lactamase activity were adapted for rapid diagnosis in vitro. These tests were done in vitro in an area of high prevalence for PPNG on males with clinically uncomplicated gonococcal urethritis. The acidometric technique failed to give a positive result. The rapid chromogenic cephalosporin technique had a 50% correlation with standard diagnostic procedures. The failure of these two rapid diagnostic techniques is thought to be due to inadequate numbers of gonococcal organisms present on the urethral swabs. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1982
Accession Number
ADA121112

Entities

People

  • Earl A. Edwards
  • Eric J. Mueller Ii
  • Michael E. Kilpatrick

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  • Naval Health Research Center

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