Acute Dermal Toxicity of CHF1, CHR2 and Saline in Rabbits.

Abstract

The acute dermal toxicity potential of CHF1 and CHR2 was determined in rabbits using abraded skin sites and plastic covering over the exposed areas for 24 hrs. No animals died. Skin irritation was greatest in the flank regions, probably due to gravity accumulation and pressure due to skin folds and adhesive bandages. These compounds should be exposed to further toxicological testing for human use potential. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1982
Accession Number
ADA121944

Entities

People

  • John T. Fruin
  • Martha A. Hanes
  • Paul W. Mellick

Organizations

  • Letterman Army Hospital

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Bandages
  • Biological Sciences
  • Biomedical Research
  • Boiling Point
  • Cells
  • Ear
  • Environmental Protection
  • Health Services
  • Insect Repellents
  • Medical Personnel
  • Military Research
  • Skin Diseases
  • Tissues
  • Toxicity
  • United States Government

Fields of Study

  • Medicine

Readers

  • Toxicology/Environmental Toxicology