Inhibition of RNA Viruses In Vitro and in Rift Valley Fever-Infected Mice by Didemnins A and B

Abstract

Didemnins, a new class of depsipeptides isolated from a Caribbean tunicate, have been shown to have potent antiviral activity against a broad range of RNA viruses in virto. Didemnins A and B both protected mice against a lethal challenge of Rift Valley fever virus.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1982
Accession Number
ADA123081

Entities

People

  • John W. Huggins
  • Kenneth L. Rienehart
  • Peter G. Canonico
  • Wallace L. Pannier

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anti-Infective Agents
  • Antiviral Agents
  • Arbovirus Infections
  • Biological Products
  • Biomedical Research
  • Chemotherapy
  • Infection
  • Microbiology
  • Rift Valley Fever
  • Rift Valleys
  • Rna Viruses
  • Sodium Compounds
  • Tissue Culture
  • Valleys
  • Viruses
  • Yellow Fever

Readers

  • Aquatic Ecology
  • Virology (or Medical Virology).