Stereotypic Responses to Infection and Inflammation: Probable Activation of Phagocytic Cells

Abstract

There is a sequence of stereotypic metabolic changes in rats subjected to inflammation or infection. In each stress, rats respond with increases in body temperature and plasma insulin and with decreases in plasma zinc, ketone bodies, and free fatty acids. The data suggest that infection or inflammation causes an activation of phagocytic cells and also that leukocytic endogenous mediator, when injected into rats, causes some of the same alterations. Rats doubly vagotomized respond to infection in the same fashion as intact rats.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1982
Accession Number
ADA123107

Entities

People

  • Harold A. Neufeld
  • Judith G. Pace

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Amino Acids
  • Arbovirus Infections
  • Bacterial Infections
  • Blood
  • Body Temperature
  • Cells
  • Equine Encephalitis
  • Fatty Acids
  • Infection
  • Infectious Diseases
  • Inflammation
  • Insulin
  • Ketones
  • Laboratory Animals
  • Nervous System
  • United States
  • Wound Infections

Fields of Study

  • Biology
  • Medicine

Readers

  • Analytical Chemistry
  • Cardiovascular Physiology
  • Immunology and Pathology