Investigations of Cross Immunity between Leishmania tropica (Jericho) and Leishmania braziliensis in Experimentally Infected Mystromys albacaudatus.
Abstract
The purpose of this report is to bring to attention the results of investigations dealing with possible cross immunity between L. tropica and L. braziliensis panamensis in an animal model. At this point in time, it would appear that there is some evidence that cross immunity does exist utilizing M. albacaudatus as an animal model. If suitable experimental animals are successfully vacinated with promastigotes of L. tropica (jericho) solid immunity will develop to challenge L. braziliensis or L. braziliensis panamensis? Part of this hypothesis is supported by the work of Lainson and Bray (1966) as mentioned above and part by the rich history of the use of related species of parasites or species with reduced virulence to prevent disease.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1981
- Accession Number
- ADA123171
Entities
People
- Bruce E. Beacham
Organizations
- University of Virginia