The Identification of a Legionella pneumophila Toxin with in vivo Lethality

Abstract

This chapter reports the demonstration of a low molecular weight protein toxin derived from a cell-free extract of sonicated L. pnemophila. The antigenic relationship of this toxin with a similar extract, obtained from a newly discovered, but genetically unrelated, gram-negative rod termed the Pittsburgh pneumonia agent, is also shown.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1980
Accession Number
ADA123370

Entities

People

  • Kenneth W. Hedlund
  • Robert Larson

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

DTIC Thesaurus Topics

  • Acids
  • Animals
  • Antibodies
  • Blood
  • Blood Proteins
  • Cells
  • Diseases And Disorders
  • Filtration
  • Laboratory Animals
  • Lethal Dosage
  • Lethality
  • Materials
  • Molecular Weight
  • Proteins
  • Rodents
  • United States
  • Vaccines

Fields of Study

  • Biology

Readers

  • Microbial Pathology

Technology Areas

  • Biotechnology