Synthesis of Azuloquinones as an Experimental Determination for a Theoretical Prediction.
Abstract
Quinones are chemical compounds utilized throughout naturally occurring biological systems in energy-transferring reduction/oxidation reactions. Quinones are also being tested in the area of anti-tumor agents. Azuloquinones are unknown quinones which may provide the specific energy that may match metabolic values. Azuloquinone is a compound that has received a great deal of attention in theoretical chemistry recently. Quantum mechanical predictions on the relative energies and stabilities of the eleven possible isomers of azuloquinone have preceded the experimental determination of the mesured energies for these compounds. The intent in this project was to synthesize several isomers of azuloquinone by simply varying the starting material conformation. Though the synthesis was not completed, there is extensive progress towards isolating isomeric azuloquinone and the route has been substantiated as a feasible way to synthesize azuloquinones.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 29, 1982
- Accession Number
- ADA124253
Entities
People
- Joseph L. Donovan
Organizations
- United States Naval Academy