The Mutagenic Potential of (E)-1,2,3,4-Tetrahydro-6-methyl-1-(2-methyl-1-oxo-2-butenyl) Quinoline (CHR 5).

Abstract

The mutagenic potential of (E)-1,2,3,4-tetrahydro-6-methyl-1-(2-methyl-1-oxo-2-butenyl) quinoline (CHR 5) was assessed by using the Ames salmonella/Mammalian Microsome Mutagenicity Assay. Tester strains TA 98, TA 100, TA 1535, TA 1537 and TA 1538 were exposed to doses ranging from .1 mg/plate to 3.2 x .00005 mg/plate. It was determined that the test substance did not have mutagenic potential.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1982
Accession Number
ADA124555

Entities

People

  • John T. Fruin
  • Leonard J. Sauers

Organizations

  • Letterman Army Hospital

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Biological Sciences
  • Biology
  • Biomedical Research
  • California
  • Cells (Biology)
  • Chemical Analysis
  • Chemistry
  • Chlorides
  • Detection
  • Genetics
  • Military Research
  • Molecules
  • Quinolines
  • Statistical Analysis
  • Toxicity
  • Verification

Fields of Study

  • Chemistry

Readers

  • Toxicology/Environmental Toxicology