Dermal Penetration and Distribution of 14C-Labeled N,N-Dipropylcyclohexane Carboxamide, AI3-36326 Study, May-October 1982. Phase 2.

Abstract

The candidate insect repellant N,N-dipropylcyclohexane carboxamide was assessed for absorption potential in rabbits and dogs by monitoring radiocarbon in excrets for 7 days following a single application. In both species, absorption occured primarily in the first 24 hours and measured 26 percent of the applied dose in rabbits and 12 percent in dogs through 7 days. No bioaccumulation in tissue specimens was noted at necropsy by this route. Absorption in man should be less than 10 percent of the applied dose. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 1983
Accession Number
ADA125214

Entities

People

  • Hubert L. Snodgrass Jr.

Organizations

  • United States Army Medical Command

Tags

DTIC Thesaurus Topics

  • Absorption
  • Adrenal Glands
  • Alcohols
  • Animals
  • Bone Marrow
  • Bones
  • Chemical Synthesis
  • Chemistry
  • Endocrine Glands
  • Glands
  • Health Services
  • Hygiene
  • Insect Repellents
  • Medical Personnel
  • New England
  • Pest Control
  • United States

Readers

  • Mathematics or Statistics
  • Toxicology/Environmental Toxicology