Mass Spectrometric Rapid Diagnosis of Infectious Diseases.

Abstract

Using new chemical procedures, mass spectrometric instrumentation and appropriate computerized data analysis, the diagnosis of a number of infectious diseases, through the molecular weight profile of neutral metabolites urine, was demonstrated. Longitudinal studies on human volunteers infected with sandfly fever showed the appearance of a characteristic pattern prior to the onset of clinical symptoms which persisted some time after the symptoms have subsided. Tissue cultures infected with polio virus exhibited a characteristic pattern demonstratable within 5 hrs from infection.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1980
Accession Number
ADA126762

Entities

People

  • James Mcreynolds
  • Michael Anbar
  • Michael Scanlon
  • Robert Abbott
  • William Rieth

Organizations

  • University at Buffalo

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Data Analysis
  • Data Science
  • Discriminant Analysis
  • Diseases And Disorders
  • Health Services
  • Infection
  • Infectious Diseases
  • Information Science
  • Liver Diseases
  • Mass Spectrometry
  • Medical Personnel
  • Molecular Weight
  • Phlebotomus Fever
  • Spectrometers
  • Statistical Analysis
  • Tissue Culture
  • Viruses

Fields of Study

  • Medicine

Readers

  • Infectious Disease/Epidemiology
  • Oncology and Biomarker-Based Cancer Detection.
  • Toxicology/Environmental Toxicology