Quantitative Studies of Microembolization in Man during Surgical Trauma.
Abstract
The present report describes recently completed studies of microembolization and alterations in platelet aggregation resulting from surgical trauma. A study of cyanotic congenital heart disease patients revealed an inverse relationship between the hematocrit and the mean size of platelet aggregates that could be induced in the patients blood in vitro by adenosine diphosphate. Another study observed the effects of changes in PaC02 on tissue oxygenation of patients under-going cardiopulmonary bypass while temperature, systemic blood flow and peripheral tissue oxygen delivery remained constant. Systemic oxygen consumption fell as the PC02 was increased from 35 to 40 mmHg, however, blood lactate remained constant and a metabolic adicosis did not develop. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 01, 1979
- Accession Number
- ADA128660
Entities
People
- R. Thomas Solis
Organizations
- Baylor College of Medicine