Mutagenic Potential of 4-Nitrophenyl Methyl (Phenyl) Phosphinate Using the Drosophila melanogaster Sex-Linked Recessive Lethal Test.

Abstract

4-Nitrophenyl methly (phenyl) phosphinate (tw011) is being considered as a prophylactic agent in anticholinesterase poisoning. This compound was tested for mutagenic activity using Drosophila melanogaster Sex-Linked Recessive Lethal assay. It was found non-mutagenic after 72-hour feeding exposures to 0.002 and 0.0025 mM of tw011.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1983
Accession Number
ADA129183

Entities

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  • Nelson R. Powers

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  • Letterman Army Hospital

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  • Biomedical

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  • Enzyme Inhibitors
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  • Poisoning
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