Mediators of Fever and Muscle Proteolysis

Abstract

The accelerated catabolism of skeletal-muscle protein that accompanies severe trauma or infection can now be ascribed to the actions of endogenously produced mediators. Two noteworthy studies described in this issue of the Journal have identified these actions by using in vitro preparations of rat skeletal muscle in a bioassay. Rates of proteolysis in muscle preparations were determined by measuring the release of free amino acid into the medium.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1982
Accession Number
ADA129460

Entities

People

  • William R. Beisel

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Bioassay
  • Blood
  • Blood Proteins
  • Branched-Chain Amino Acids
  • Cells
  • Cellular Structures
  • Infection
  • Muscle Cells
  • Muscle Proteins
  • Muscles
  • New England
  • Phagocytes
  • Proteins
  • Skeletal Muscle
  • United States
  • Wound Infections

Fields of Study

  • Medicine

Readers

  • Molecular and Cellular Biochemistry
  • Theoretical Analysis.
  • Trauma Surgery or Emergency Medicine.