Subeschar Treatment of Burn-Wound Infection

Abstract

Within a 24-month period, 454 patients were admitted with burns (average size, 33% of the total body surface [TBS]). Wound infection developed in 19, who subsequently were treated with subeschar antibiotics. The average burn size in those 19 patients was 63% of the TBS, with an average full-thickness injury of 47%. Five (26%) of the 19 survived, giving a wound clearance rate of 52.6%. The five surviving patients (average burn size, 59% TBS) underwent excision of infected tissue, with split-thickness cutaneous autograft closure of the burn wound, after the course of subeschar antibiotic infusion. All surviving patients were infected with Psuedomonas aeruginosa. Subeschar infusion of semisynthetic penicillins, therefore, is an effective adjunct in the care of the patient with pseudomonas burn-wound infection.

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 1983
Accession Number
ADA131028

Entities

People

  • Basil A. Pruitt Jr.
  • Cleon W. Goodwin Jr.
  • William F. McManus

Organizations

  • United States Army Institute of Surgical Research

Tags

DTIC Thesaurus Topics

  • Animals
  • Anti-Bacterial Agents
  • Bandages
  • Blood
  • Burns
  • Chemotherapy
  • Health Services
  • Hemorrhagic Shock
  • Infection
  • Microorganisms
  • Sepsis
  • Therapy
  • Wound Infections
  • Wounds And Injuries

Fields of Study

  • Medicine

Readers

  • Immunology
  • Mathematics or Statistics
  • Trauma Surgery or Emergency Medicine.