Acute Intramuscular Toxicity (LD50) of 1,1'-Methylenebis (4- (Hydroxyimino) Methyl) Pyridinium Dibromide, (MMB-4) in Male Mice

Abstract

The acute intramuscular toxicity of MMB-4 was determined in male ICR mice by using the single dose method. LD(1), LD(50), and LD(95) with their 95% confidence limits were calculated by probit analysis. The LD(50) was 448 mg/kg with the 95% confidence limit (398 mg/kg, 506 mg/kg). The MMB-4 formulation falls in the very toxic range.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1983
Accession Number
ADA131940

Entities

People

  • Craig W. White
  • Leonard J. Sauers
  • Martha A. Hanes

Organizations

  • Letterman Army Hospital

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Anesthesia
  • Biological Sciences
  • Biomedical Research
  • California
  • Chemical Warfare Agents
  • Confidence Limits
  • Factor Analysis
  • Lethal Dosage
  • Medical Personnel
  • Military Research
  • Physicians
  • Quality Control
  • Scientific Research
  • Toxicology
  • United States
  • United States Government

Fields of Study

  • Chemistry
  • Medicine

Readers

  • Neurotoxicology
  • Toxicology/Environmental Toxicology