Primary Eye Irritation Potential of the Holston Compounds: Virgin DMSO (Dimethyl Sulfoxide), DMSO Recycle Solvent, and DMSO Evaporator Sludge.

Abstract

The primary eye irritation potential of the Holston Compounds (Virgin DMSO, DMSO Recycle Solvent, and DMSO Evaporator Sludge) was tested by placing these materials in the conjunctival cul-de-sac of rabbit eyes. The study was conducted in compliance with the Good Laboratory Practice Regulations. All of the Dimethly Sulfoxide compounds tested produced irritation of the conjunctiva early in the study, but the level of severity did not meet the criteria for positive eye irritants.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1983
Accession Number
ADA132407

Entities

People

  • Craig W. White
  • John T. Fruin
  • Thomas P. Kellner

Organizations

  • Letterman Army Hospital

Tags

DTIC Thesaurus Topics

  • Animals
  • Bioengineering
  • Biological Sciences
  • Biomedical Research
  • California
  • Engineering
  • Eye
  • Health
  • Irritants
  • Laboratory Animals
  • Materials
  • Military Research
  • Scientific Research
  • Ticks
  • Toxicology
  • United States
  • United States Government

Readers

  • Environmental Engineering.
  • Toxicology/Environmental Toxicology